Endocrine Abstracts

A 75-year old gentleman presented with symptoms of increasing lethargy, loss of appetite associated with weight loss and constant micturition. A CT scan showed extensive peritoneal mass in the lower abdomen and pelvis with disseminated intraperitoneal malignancy. A CT guided biopsy confirmed a poorly differentiated tumour. Immunohistochemistry showed that all the cytokeratin markers were negative, but vimentin was positive and CD117 (c-kit) was strongly positive, indicating th...

Background: Current UK guidelines for the Use of Thyroid Function Tests provide specific recommendations for the use of thyroid function tests in inpatients. Isolated alterations in TSH occur in 15% of inpatients and <2% will have underlying thyroid disorder. Thyroid function should be repeated every 4–6 weeks when changing thyroxine replacement dose or when commencing thionamides.Aim: To identify the indications and frequency of thyroid tests i...

Introduction: Acromegaly is commonly associated with numerous cardiovascular manifestations such as left ventricular hypertrophy, hypertension and ischemic heart disease. However, initial presentation with dilated cardiomyopathy is relatively rare. Dilated cardiomyopathy in patients with acromegaly usually result from an extended and excessive exposure of the myocardium to growth hormone.Case presentation: 51-year-old female with background medical histo...